Camshia Combination Tablets HD for hypertension (candesartan, amlodipine)

What are Camshia Combination Tablets HD for hypertension? 

Camshia tablets, a combination medication containing candesartan cilexetil and amlodipine besilate, are widely prescribed for the management of hypertension, a common cardiovascular condition. Camshia Combination Tablets HD contain a higher dosage of active principles, 8 mg of candesartan cilexetil and 5 mg of amlodipine in each tablet. 

Candesartan cilexetil is an angiotensin II receptor blocker (ARB) that acts by blocking the binding of angiotensin II to its receptors, resulting in vasodilation and a reduction in blood pressure. It primarily affects the renin-angiotensin-aldosterone system (RAAS), leading to decreased vasoconstriction and reduced sodium and water retention, thereby lowering blood pressure. Amlodipine besilate, on the other hand, is a calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle cells, leading to relaxation of the arterial walls and subsequent vasodilation.

Combining candesartan cilexetil and amlodipine besilate in Camshia tablets provides a synergistic effect in reducing blood pressure. This dual action targets both the RAAS and calcium-mediated vasoconstriction pathways, enhancing their individual antihypertensive effects. The result is a more comprehensive reduction in blood pressure levels.

The effectiveness of Camshia tablets in managing hypertension has been well-documented in clinical trials and real-world settings. Patients with hypertension who are prescribed Camshia tablets often experience significant reductions in both systolic and diastolic blood pressure, bringing their values within the recommended target range. 

Active principles: candesartan cilexetil, amlodipine besilate

Amount: 100 tablets 

Maker: Daiichi Sankyo Espha Co., Ltd.,  Sandoz K. K., Japan

Indications: treatment of hypertension

How to take

Adults should take 1 tablet at a time, once a day. 

Contraindications: do not use for the following patients:

• patients with renal disorder, hepatic disorder, cardiac failure, hyperkalemia, hyponatremia,
• patients who are on schedule of surgery,
• patients on dialysis or a regimen of low-salt diet,
• pregnant, possibly pregnant or breastfeeding women. 

Important information

As this medicine may cause dizziness, patient should pay close attention when working at heights, driving a car or operating dangerous machinery.

Avoid taking grapefruit juice while taking medicine.

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.