Vitamin K capsules (menaquinone) from Japan

What are Vitamin K capsules (menaquinone)?

Vitamin K plays a crucial role in bone health and calcium regulation, making it a valuable component in preventing bone fractures and improving calcium accumulation within the bones. The mechanism of action of Vitamin K in this context primarily involves its influence on two key proteins: osteocalcin and matrix Gla protein (MGP).

Osteocalcin is a protein produced by osteoblasts, the cells responsible for bone formation. Vitamin K activates osteocalcin by facilitating its carboxylation, which allows it to bind to calcium ions more effectively. This process enhances the mineralization of the bone matrix, making bones stronger and less susceptible to fractures. Without adequate Vitamin K, osteocalcin remains inactive, leading to decreased calcium binding and weaker bones.

On the other hand, matrix Gla protein (MGP) is a protein that inhibits the calcification of soft tissues, such as blood vessels and cartilage. Vitamin K activates MGP by carboxylating it, preventing the unwanted accumulation of calcium in these tissues. This mechanism ensures that calcium is directed towards the bones, where it is needed for structural integrity.

Effectiveness of Vitamin K capsules in improving calcium accumulation and preventing bone fractures is supported by various studies. Research has shown that individuals with higher dietary intake of Vitamin K tend to have better bone density and reduced fracture risk. Moreover, supplementation with Vitamin K has been particularly beneficial for people with osteoporosis, a condition characterized by low bone density and increased fracture susceptibility. Vitamin K, in the form of capsules or dietary supplements, can help restore the balance between bone formation and resorption, ultimately leading to stronger bones.

Active principles: 

• vitamin K 67.4 mcg, 
• vitamin C 30 mg, 
• vitamin D 2.5 mcg,
• casein phosphopeptide 40mg.

Amount: 60 soft capsules

Maker: DHC Corporation, Tokyo, Japan

Indications: 

• preventing bone fractures,
• strengthening bones

How to take

Take 2 capsules a day with water or warm water. 

Contraindications: pregnant and breastfeeding women should consult with their doctor before use. Patients who take anticoagulants should not take this medicine as it may lessen the effectiveness of anticoagulants. 

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.