Urece tablets 2 mg for gout and hyperuricemia (dotinurad)
What are Urece tablets 2 mg for gout and hyperuricemia (dotinurad)?
Urece tablets, housing the active compound dotinurad, present a promising remedy for individuals plagued by gout and hyperuricemia. The functioning of Urece tablets is straightforward yet impactful: they inhibit uric acid reabsorption in the kidneys, thus promoting its excretion through urine and consequently reducing blood uric acid levels.
Dotinurad, the principal ingredient in Urece tablets, originated in Japan and gained medical approval in 2020. Since then, it has emerged as a pivotal treatment for those grappling with gout and hyperuricemia, its efficacy validated through rigorous clinical trials.
In a notable study titled "Efficacy of dotinurad, a selective urate reabsorption inhibitor, in patients with hyperuricemia/gout and cardiovascular risks: a pooled analysis of phase II/III studies," Japanese researchers highlighted dotinurad's effectiveness. They observed not only a significant reduction in serum uric acid levels in hyperuricemic patients but also promising outcomes for individuals with multiple cardiovascular risk factors. Such findings hold considerable significance, especially in cardiovascular health, as dotinurad's potential to manage hyperuricemia while addressing cardiovascular risks presents new possibilities for patient care.
For those seeking dependable treatment for gout and hyperuricemia, Urece tablets containing dotinurad offer a compelling option. Backed by solid scientific research and clinical validation, these tablets provide hope and relief to individuals facing the challenges of these conditions.
In summary, the introduction of dotinurad treatment through Urece tablets signifies a significant leap in gout and hyperuricemia management. Its established efficacy and mode of action underscore its importance in modern medical practice, offering patients a safe and efficient solution for these conditions.
Active principles: dotinurad
Amount: 100 tablets
Indications: gout and hyperuricemia
How to take: For adults, begin with a starting dose of 0.5 mg of the active ingredient once daily. Adjustments to the dosage can be made based on your blood uric acid levels as necessary. Following two weeks, the dosage may be raised to 1 mg once daily, with a subsequent increase to 2 mg once daily for maintenance after six weeks. Dosage modifications should be made in accordance with your individual condition, ensuring not to exceed 4 mg once daily. Each tablet of this preparation contains 2 mg of the active ingredient. Should you experience a gout attack (pain) while using this medication, refrain from altering your dosage or discontinuing use.
Contraindications and precautions: If your urine exhibits acidity, you may be prone to experiencing symptoms such as urinary stones, subsequent hematuria, and renal colic. To prevent this, it's advisable to drink plenty of water to boost urinary output and promote urine alkalinity. Do not expose to sunlight or heat. If allergic symptoms occur, discontinue use. Do not use in the following cases:
- urinary stone,
- renal dysfunction,
- liver dysfunction,
- pregnancy or breastfeeding.