Tramal tablets 50 mg for cancer pain, postoperative and chronic pain (tramadol hydrochloride, Ultram)
What are Tramal tablets 50 mg for cancer pain and chronic pain (tramadol hydrochloride, Ultram)?
Tramal tablets contain tramadol hydrochloride, a potent opioid analgesic. With a history spanning six decades, it continues to be widely prescribed in numerous countries worldwide. Tramadol hydrochloride operates by binding to opioid receptors and inhibiting the reuptake of monoamines.
Tramal tablets demonstrate effectiveness in alleviating severe pain, such as cancer-related pain, postoperative pain, and chronic pain unresponsive to non-opioid analgesics. Research has indicated that the metabolites of the active ingredient are water-soluble and are excreted via the kidneys, enabling the use of reduced doses even in patients with kidney or liver conditions.
Active principles: tramadol hydrochloride
Amount: 100 tablets
Maker: Nippon Shinyaku Co., Ltd., Kyoto, Japan
Indications: relieving severe pain, including cancer pain, postoperative pain and chronic pain that is non-responsive to non-opioid analgesics
How to take
Adults should take 2-6 tablets (100-300 mg of the active principle) a day, in 4 divided doses. The interval between the doses should be 4-6 hours. Your doctor in may adjust the dosage according to the disease, age or symptoms. But the maximum dose of 100 mg at a time, 400 mg a day, should not be exceeded. For elderly people over 75 years old, the daily dose is usually up to 300 mg.
In case of acute worsening of cancer pain, patients should take 1/8 to 1/4 of their regular daily dose at a time as a rescue dose.
If the patient is taking this medicine for the first time, it is recommended to start with 25 mg. The tablets should be increased or decreased by the step of 25 mg. If a patient no longer needs this medicine, the dose should be reduced gradually.
When used for chronic pain, if the expected effect is not obtained in 4 weeks after the start of administration, a change to another treatment should be considered. When using for cancer pain, if the pain cannot be relieved even with 300 mg a day, a change to a strong opioid analgesic such as morphine should be considered.
Please note that this preparation contains 50 mg of the active ingredient in one tablet.
Contraindications: do not use for the following patients:
- patients with acute intoxication caused by alcohol,
- patients taking sleeping pills, painkillers, opioid pain relievers or psychotropic drugs,
- patients with epilepsy or head injury with inadequate therapeutic management,
- patients who have used other drugs like monoamine oxidase inhibitor, drinking acid salt (Azilect), saffinamide mesylate (Ekfina) or nalmefene hydrochloride hydrate within the past 2 weeks,
- children under 12 years old,
- patients under the age of 18 with obesity, obstructive sleep apnea syndrome or severe lung disease,
- pregnant or breastfeeding women.
As this medicine may cause dizziness or sleepiness, patient should avoid operating dangerous machinery, working at heights or driving a car while taking this medicine.
Avoid drinking alcohol while taking this medicine as it may intensify medical effects and adverse reactions.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.