Toledomin tablets 25 mg for depression (milnacipran, Ixel, Savella, Dalcipran)

What are Toledomin tablets 25 mg for depression (milnacipran, Ixel, Savella, Dalcipran)?

Toledomin tablets, containing milnacipran, are classified as a Selective Serotonin and Norepinephrine Reuptake Inhibitor (SNRI) and are commonly prescribed for the management of depression. The mechanism of action of Toledomin tablets involves the modulation of intracerebral neurotransmission to alleviate depressive mood and associated anxiety. This medication works by targeting specific neurotransmitters in the brain, particularly serotonin and norepinephrine, which play a pivotal role in mood regulation.

The fundamental principle behind SNRIs like milnacipran is the inhibition of the reuptake of serotonin and norepinephrine in the synaptic cleft, allowing these neurotransmitters to remain active for a longer duration. By doing so, Toledomin tablets promote a balanced and more sustained neurotransmission in the central nervous system, ultimately leading to improved mood and reduced anxiety in individuals suffering from depression.

Research and clinical studies have indicated that Toledomin tablets are highly effective in the treatment of depression and depressive states. 

Active principles: milnacipran hydrochloride

Amount: 100 tablets

Maker: Asahi Kasei Pharma Corporation, Tokyo, Japan

Indications: treatment of depression and depressive state 

How to take

Adults should start with 25 mg of the active principle once a day, after meals, as the initial dosage. Then the dosage should be gradually increased up to 100 mg a day, divided into 2-3 times, after meals. Your doctor may adjust the dosage according to your age or symptoms.

Elderly patients should start with 25 mg of the active principle once a day, after meals, as the initial dosage. Then the dosage should be gradually increased up to 60 mg a day, divided into 2-3 times, after meals. 

Please note that this medicine contains 25 mg of the active principle in 1 tablet. 

Contraindications: do not use for the following patients:

pregnant or breastfeeding women,

patients with urinary retention due to prostate disease, dysuria, glaucoma, elevated intraocular pressure, 

patients with cardiac disease or hypertension, 

patients with liver or renal dysfunction, 

patients with convulsive disorders such as epilepsy or its history, 

patients with manic-depressive illness, suicidal thought or suicide attempt or its history, organic brain disorder, predisposition to schizophrenia, highly impulsive comorbid disorders. 

Important information

Avoid taking alcohol while taking this medicine. 

As this medicine may cause drowsiness or dizziness, patient should pay close attention when operating dangerous machinery, driving a car or working at heights. 

As this medicine may cause elevation of blood pressure, blood pressure and the pulse rate should be measured regularly. 

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.