Tizanidine operates as an alpha-2 adrenergic receptor agonist, primarily exerting its influence on the central nervous system. This modulation within the central nervous system plays a crucial role in dampening neurotransmission signals, thereby alleviating excessive muscular tension.
Tizanidine tablets have demonstrated effectiveness in addressing myotonic states stemming from conditions like neck-shoulder-arm syndrome and low back pain. Moreover, they are utilized in the management of spastic paralysis, encompassing disorders such as cerebrovascular issues and posttraumatic complications. Notable comparative studies indicate that the therapeutic efficacy of tizanidine closely resembles that of baclofen or diazepam, while notably exhibiting a higher level of tolerability.
Through its mechanism of action, tizanidine stands as a beneficial option for individuals grappling with musculoskeletal discomfort and spasticity-related challenges. Its ability to selectively target the central nervous system's signaling pathways provides a valuable avenue for addressing these conditions, offering patients a potential solution with balanced efficacy and tolerability profiles.
Active principles: tizanidine
Amount: 100 tablets
Maker: Nichi-Iko Pharmaceutical Co., Ltd., Toyama, Japan
Indications:
For myotonic state: adults should take 1 tablet (1mg of active principle) at a time, 3 times a day after meals.
For spastic paralysis: adults should start with taking 1 tablet at a time, 3 times a day after meals, as an initial dose. Then the dosage may be gradually increased up to 2-3 tablets at a time, 3 times a day.
Your doctor may adjust the dosage according to disease, age and symptoms in any case.
Contraindications: do not use for pregnant or breastfeeding women. Do not use for patients with liver disorders.
As this medicine may cause sleepiness or dizziness, patient should avoid driving a car, operating dangerous machinery or working at heights.
Avoid drinking alcohol while taking the medicine as it may enhance the side effects. Smoking also may affect the efficacy of this medicine.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.
