Takecab tablets 10 mg for ulcer and reflux esophagitis (vonoprazan fumarate)

What are Takecab tablets 10 mg for ulcer and reflux (vonoprazan fumarate)?

Takecab tablets are formulated with vonoprazan fumarate, an innovative potassium-competitive acid blocker, marking the pioneering entry in its class. This compound operates by competitively inhibiting the proton pump, employing an ion-competitive mechanism to effectively curtail the secretion of gastric acid. Clinical investigations have demonstrated that the administration of Takecab tablets swiftly elevates intragastric pH within just 4 hours after the initial consumption. Moreover, throughout the treatment regimen, these tablets substantially prolong the duration of optimal intragastric pH levels.

Indicated for a range of conditions including gastric and duodenal ulcers, as well as reflux esophagitis, Takecab tablets offer efficacious therapy. Particularly noteworthy is their capacity to prevent the recurrence of gastric and duodenal ulcers induced by low-dose aspirins or other nonsteroidal anti-inflammatory drugs. Additionally, Takecab tablets can be employed synergistically with clarithromycin or amoxicillin for the eradication of Helicobacter pylori infections.

Active principles: vonoprazan fumarate

Amount: 100 tablets

Maker: Takeda Pharmaceutical Co. Ltd., Tokyo, Japan

Indications:

• treatment of gastric ulcer,
• treatment of the duodenal ulcer,
• treatment of reflux esophagitis,
• suppression of recurrence of gastric/duodenal ulcer associated with low-dose aspirin or nonsteroidal anti-inflammatory drug medication.

How to take

Gastric/duodenal ulcer or reflux esophagitis: for adults should take 2 tablets (20 mg of vonoprazan) at a time, once a day. Duration of taking the medicine is up to 8 weeks for gastric ulcer; 6 weeks for duodenal ulcer; 4 weeks for reflux esophagitis, but if the effect is insufficient, the treatment may be continued for up to 8 weeks.

Maintenance therapy for repeatedly relapsing reflux esophagitis: adults should take 1 tablet (10 mg of vonoprazan) at a time, once a day. If the effect is insufficient, the dosage may be increased to 2 tablets (20 mg) at a time.

Suppression of recurrence of gastric/duodenal ulcers associated with low-dose aspirin or non-steroidal anti-inflammatory drug therapy: adults should take 1 tablet (10 mg of vonoprazan) at a time, once a day.

Contraindications: do not use for pregnant or breastfeeding women. Do not use for patients with liver or renal disorder.

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.