Stomin A tablets, designed for the treatment of tinnitus, incorporate two active ingredients: nicotinamide and papaverine hydrochloride. These components work in tandem to address the underlying factors contributing to tinnitus, providing a potential solution to this auditory condition.
The mechanism of action of Stomin A tablets revolves around their ability to enhance blood circulation within the inner ear while also mitigating the destabilizing effects of noise-induced stimulation on electrolyte levels. Nicotinamide, a form of vitamin B3, is recognized for its role in promoting blood flow. When administered in Stomin A tablets, it aids in vasodilation, widening the blood vessels that supply the inner ear. This increased blood flow fosters improved oxygen and nutrient delivery to the auditory structures, which can contribute to the reduction of tinnitus symptoms.
Papaverine hydrochloride, the second active principle in Stomin A tablets, complements nicotinamide's action by further facilitating vasodilation. This compound works by relaxing the smooth muscles lining the blood vessels, allowing them to expand more readily. This relaxation effect promotes enhanced blood flow, especially in the microvascular network of the inner ear. Consequently, it contributes to a more stabilized auditory environment.
One notable effect of the combined action of nicotinamide and papaverine hydrochloride is the mitigation of fluctuations in electrolyte levels induced by noise stimulation. Noise exposure, a common trigger for tinnitus, can lead to irregular shifts in the concentration of electrolytes within the inner ear. This disruption can result in abnormal nerve signaling and contribute to tinnitus symptoms. By preventing these fluctuations, Stomin A tablets aim to alleviate the severity and frequency of tinnitus episodes.
Research studies have indicated that Stomin A tablets possess a comparative advantage over medications containing only nicotinamide. While nicotinamide alone exhibits an effectiveness rate of approximately 50.9% in addressing tinnitus cases, the combined formulation of Stomin A tablets has demonstrated an ability to elevate this effectiveness to around 67.3%. This enhancement in efficacy underscores the synergy between nicotinamide and papaverine hydrochloride in tackling the multifaceted nature of tinnitus.
Active principles: nicotinamide, papaverine hydrochloride
Amount: 100 tablets
Maker: Zonnebodo Pharmaceutical, Tokyo, Japan
Indications: tinnitus due to inner ear or central neurological disorders
Adults should take 2 tablets 3 times a day after meals. Your doctor can adjust the dosage according to your symptoms.
Contraindications: do not use for the following patients:
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.
