Simvastatin tablets 5 mg for hyperlipidemia and familial hypercholesterolemia (statin, Zocor, Zocord, Lipovas)

What are Simvastatin tablets 5 mg for hyperlipidemia, familial hypercholesterolemia (statins, Zocors, Zocords, Lipovas)?

Simvastatin tablets, containing 5 mg of the active ingredient simvastatin, are commonly prescribed to address hyperlipidemia and familial hypercholesterolemia. The mechanism of action of simvastatin involves its role as a HMG-CoA reductase inhibitor, which is an enzyme crucial for cholesterol synthesis in the liver. By inhibiting this enzyme, simvastatin effectively reduces the production of cholesterol, leading to decreased levels of LDL (low-density lipoprotein) cholesterol, commonly referred to as "bad" cholesterol.

Clinical studies have demonstrated the effectiveness of simvastatin in lowering LDL cholesterol levels. It has also shown the ability to modestly increase levels of HDL (high-density lipoprotein) cholesterol, known as "good" cholesterol. The overall impact is a favorable alteration in the LDL-to-HDL cholesterol ratio, which is considered beneficial for cardiovascular health.

For individuals with hyperlipidemia and familial hypercholesterolemia, conditions characterized by elevated cholesterol levels, Simvastatin tablets can be particularly beneficial. By reducing LDL cholesterol, simvastatin helps mitigate the risk of atherosclerosis and its associated complications, such as coronary artery disease and strokes. It's important to note that simvastatin is typically prescribed as part of a comprehensive treatment plan, which may include dietary changes and lifestyle modifications.

Active principles: simvastatin

Amount: 100 tablets

Maker: Takeda Pharmaceutical Co., Ltd./ Sawai Pharmaceutical Co., Ltd., Japan

Indications: treatment of hyperlipidemia and familial hypercholesterolemia

How to take

Adults should take 1 tablet (5 mg of the active principle) at a time once daily. Your doctor may adjust the dosage depending on your age and other symptoms. The dosage can be increased up to 4 tablets (20 mg) per day if the LDL-cholesterol levels are not reduced.

Contraindications: do not use for pregnant or breastfeeding women. Do not use for patients with liver or renal disorder. 

Important information

Do not consume grapefruit juice during treatment. Follow the directions for diet and exercise therapy.

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.