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Selara Tablets 50mg X 100 tablets (hypertension, heart failure)

Selara Tablets 50mg X 100 tablets (hypertension, heart failure)

Product Code:
USD 179

What are Selara Tablets 50 mg for hypertension?

Selara tablets are a medication whose active ingredient is eplerenone. Eplerenone is a selective aldosterone receptor antagonist, commonly referred to as a mineralocorticoid receptor antagonist (MRA). It exerts its effects by binding to the mineralocorticoid receptors in the body, specifically the aldosterone receptors, which are found in various tissues, including the heart, blood vessels, and kidneys.

The primary mechanism of action of Selara tablets involves blocking the binding of aldosterone to its receptors. Aldosterone is a hormone produced by the adrenal glands that plays a key role in regulating sodium and potassium levels in the body, as well as maintaining fluid balance. By inhibiting the effects of aldosterone, eplerenone reduces the retention of sodium and water, while promoting the excretion of potassium.

This mechanism leads to several physiological effects. Selara tablets are used primarily in the management of conditions such as hypertension and heart failure. By reducing sodium and water retention, the medication helps to decrease fluid buildup in the body, leading to a decrease in blood pressure and a potential improvement in symptoms of heart failure.

Active principles: eplerenone

Amount: 100 tablets

Maker: Viatris Pharmaceuticals Inc., Tokyo, Japan

Indications: hypertension

How to take

Adults should start with 1 tablet (50 mg of the active principle) at a time, once a day. If it is not effective enough, the dosage may be increased up to 2 tablets (100 mg) a day. However, if you take this medicine in combination with other medicinal products that suppress its metabolism, the daily dosage may not exceed 25 mg at a time, once a day. 

Contraindications: do not use for the following patients:

  • patients with hyperkalemia, 
  • patients with diabetes mellitus with microalbuminuria or proteinuria, 
  • patients with renal dysfunction or liver dysfunction,
  • pregnant or breastfeeding women. 

Important information

As this medicine may cause dizziness by rapid decrease in the blood pressure, patient should pay close attention to operating dangerous machinery, driving a car or working at heights.

Patient should avoid taking any health supplement containing St. John's wort while taking this medicine.

Blood test or liver function test should be performed periodically to avoid the occurrence of hyperkalemia, hyponatremia or liver function abnormality, 

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.

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