Rosuvastatin tablets 2.5 mg for hypercholesterolemia (statin, Crestor)

What are Rosuvastatin tablets 2.5 mg for hypercholesterolemia (statin, Crestor)?

Rosuvastatin, a synthetic medicine belonging to the statin class, exerts its cholesterol-lowering effects through a specific mechanism of action that targets the production of cholesterol in the liver. By inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the synthesis of cholesterol, Rosuvastatin effectively reduces the overall cholesterol levels in the body.

The primary effects of Rosuvastatin include lowering total cholesterol, particularly the low-density lipoprotein (LDL) cholesterol levels, which are commonly referred to as "bad" cholesterol. Moreover, the medication also exhibits the beneficial effect of increasing high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol. This HDL cholesterol plays a crucial role in transporting excess cholesterol from the blood vessels to the liver for further processing and elimination, thereby helping to reduce the risk of plaque buildup and atherosclerosis.

Another significant benefit of Rosuvastatin is its ability to decrease blood triglyceride levels. Triglycerides are a type of fat present in the blood and elevated levels are associated with an increased risk of cardiovascular disease. By lowering triglyceride levels, Rosuvastatin further contributes to cardiovascular health and reduces the risk of related complications.

Given its potent cholesterol-lowering effects, Rosuvastatin is widely recommended for individuals at high risk of cardiovascular events. It is particularly beneficial for patients suffering from hypercholesterolemia, a condition characterized by elevated levels of cholesterol in the blood. In such cases, Rosuvastatin tablets can be prescribed to help manage cholesterol levels effectively.

Clinical evidence from a comprehensive meta-review involving 108 clinical studies and over 19,000 patients has demonstrated the impressive effectiveness of Rosuvastatin in reducing cholesterol levels. The findings revealed that total cholesterol was reduced by an impressive 22.1% to 44.8%, while LDL cholesterol levels were significantly lowered by 31.2% to 60.2%. Furthermore, non-HDL cholesterol, which encompasses all cholesterol except HDL, saw a substantial reduction ranging from 28.9% to 56.7%. Additionally, Rosuvastatin effectively decreased triglyceride levels by 14.4% to 26%.

Active principles: rosuvastatin

Amount: 100 tablets

Maker: Ohara Pharmaceutical Co., Ltd. / Nipro Corporation, Japan

Indications: treatment of hypercholesterolemia

How to take

Start by taking one tablet (2.5 mg of rosuvastatin) at a time, once a day. If the dosage is insufficient or a quicker progress is desired, the dosage may be increased up to two tablets (5 mg) at a time, once a day. Your doctor may adjust the dose according to your symptoms and age. The dose may be increased if the efficacy of the medication is not sufficient after at least 4 weeks of the treatment. However, the maximum daily intake of 8 tablets (20 mg) should not be exceeded.

These tablets will dissolve in saliva once it is placed on the tongue. However, the medicine should be swallowed with enough amount of water or saliva to ensure that it doesn't get stuck in the mouth.

Contraindications: do not use for pregnant, possibly pregnant or breastfeeding women. Do not use for patients with liver disorders. 

Important information

Patient should follow the diet and exercise instructions carefully.

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.