Rocaltrol injections 1 mcg for secondary hyperparathyroidism (calcitriol, Calcijex, Decostriol, Vectical, Rolsical)

What are Rocaltrol injections 1 mcg for secondary hyperparathyroidism (calcitriol, Calcijex, Decostriol, Vectical, Rolsical)?

Rocaltrol injections contain calcitriol, the active form of vitamin D naturally synthesized in the kidneys. One of the primary actions of Rocaltrol injections is the direct and indirect suppression of the synthesis and secretion of parathyroid hormone (PTH) within the parathyroid cells. By modulating the PTH production and release, Rocaltrol helps restore the delicate balance of calcium and phosphorus in the body. As a result, it plays a crucial role in maintaining bone health and overall mineral metabolism.

Furthermore, Rocaltrol injection effectively lowers serum PTH concentrations, which is particularly significant in managing certain medical conditions like secondary hyperparathyroidism. Secondary hyperparathyroidism often occurs in patients undergoing maintenance dialysis, where the impaired kidney function disrupts the body's ability to regulate calcium and phosphorus levels. Rocaltrol's ability to reduce serum PTH concentrations contributes to improved mineral homeostasis in these individuals.

Another vital benefit of Rocaltrol injection is its capacity to increase blood calcium levels. This effect is achieved by promoting the absorption of calcium from the gastrointestinal tract, ensuring an adequate supply of calcium to support various physiological functions. Additionally, Rocaltrol enhances renal tubular reabsorption of calcium, ensuring that the kidneys efficiently retain this vital mineral rather than excreting it through urine. As a result, Rocaltrol aids in maintaining optimal calcium levels throughout the body, supporting bone health, nerve function, and muscle contraction.

Clinical studies have demonstrated the remarkable efficacy of Rocaltrol injections in treating secondary hyperparathyroidism in patients undergoing maintenance dialysis. The optimal dosage of 1 mcg of active ingredient for intravenous administration allows to reach a balance between effectively reducing serum parathyroid hormone levels and avoiding the risk of hypercalcemia, an excessive accumulation of calcium in the blood.

Active principles: calcitriol

Amount: 10 vials

Maker: Kyowa Kirin Co., Ltd., Tokyo, Japan

Indications: treatment of secondary hyperparathyroidism in patients undergoing maintenance dialysis.

How to use

For adults, inject intravenously at the end of each dialysis, 1-3 times a week.

Depending on patient’s response to treatment, this medicine may be used for a long period of time. The specific dosing schedule should be prescribed by your doctor.

Contraindications: do not use for pregnant or breastfeeding women. Do not use for patients with vitamin D intoxication.

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.