What are Recalbon tablets 1 mg for osteoporosis?
Recalbon tablets are a medication for osteoporosis that contain 1 mg of a bisphosphonate compound called minodronic acid hydrate. Bisphosphonates are substances that prevent the breakdown of bone by inhibiting the activity of osteoclasts, the cells that resorb bone. Minodronic acid hydrate works by blocking an enzyme called farnesyl pyrophosphate synthase, which is essential for the formation and function of osteoclasts. By doing so, it reduces the rate of bone resorption and preserves bone mass and quality.
Minodronic acid hydrate is a third-generation bisphosphonate that has a high potency and selectivity for bone tissue. It is 1000 times more effective than etidronic acid and 10 to 100 times more effective than alendronic acid, two other bisphosphonates, in inhibiting osteoclastic bone resorption. Recalbon tablets can effectively prevent new vertebral and nonvertebral fractures, which are common complications of osteoporosis.
Recalbon tablets are suitable for both primary and secondary osteoporosis, which are caused by different factors such as aging, menopause, or steroid use. Clinical studies have shown that minodronic acid hydrate can increase bone mineral density and strength in patients with various types of osteoporosis, such as postmenopausal osteoporosis or steroid-induced osteoporosis. Recalbon tablets can also improve the geometry and biomechanical properties of the hip, which are important determinants of fracture risk.
Active principles: minodronic acid hydrate
Amount: 100 tablets
Maker: Ono Pharmaceutical Co., Ltd., Osaka, Japan
Indications: increasing bone density and strength, preventing bone fracture.
How to take
Take 1 tablet 1 time a day with a full cup of water, strictly before the first meal or beverage of the day. At least for the first 30 minutes after taking the tablet, refrain from lying down, eating, drinking (including mineral water) or taking other medicine, except drinking usual water.
Contraindications: do not use for the following patients:
- patients with disorder that delays esophageal transit, for example, esophageal stenosis,
- patients unable to sit upright for more than 30 minutes,
- patients with hypocalcemia,
- pregnant or breastfeeding women.
Never take this medicine after consuming any food or beverages. If you missed the dose and have already had some foods and beverages, skip the missed dose and continue regular intake from the next morning.
Do not crunch or dissolve the medicine in the mouth as it might cause irritation. Maintain your oral hygiene while taking this medicine. Do not take the medicine at bedtime or before rising. Make sure to take enough calcium and vitamin D from food or vitamin supplements.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.