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Orapenem fine granules 10% for children (tebipenem pivoxil, antibiotic)

Product Code:
USD 755

What are Orapenem Fine Granules 10% for Children (tebipenem pivoxil, antibiotic)?

An active principle of Orapenem granules is tebipenem pivoxil, the first oral antibiotic of a class of carbapenems. It quickly converts into the active form in plasma or enterocytes, Orapenem fine granules have a broad range of actions. Usually, this medicine is prescribed for the treatment of sinusitis, otitis media, and pneumonia in children. Tebipenem pivoxil is often used in cases of failure with other antibiotics as it works effectively even for bacteria resistant to other antibiotics, including Gram-negative multidrug-resistant pathogens, such as quinolone-resistant Enterobacteriaceae. This medicine provides a rapid effect, clinical studies proved that in children with community-acquired pneumonia tebipenem pivoxil significantly lowers body temperature on the day following initial administration and reduces leukocyte counts and C-reactive protein levels by day 2-4 of the treatment. 

Active principles:  tebipenem pivoxil

Amount: 120 packets * 0.5 g

Maker: Meiji Seika Pharma Co., Ltd., Tokyo, Japan


  • pneumonia,
  • otitis media,
  • sinusitis,
  • quinolone-resistant Enterobacteriaceae.

How to take

Children should take 0.04 grams per kilogram of body weight, 2 times a day, after meals. Your pediatrician can increase the dose to 0.06 grams per kg of body weight if needed. 

The standard duration of the treatment is 7 days or less.

Contraindications: do not use for the following patients:

  • pregnant or breastfeeding women,
  • patients with renal disease, 
  • patients suffering from poor nutrition or ingestion, or in poor general health,
  • patients with convulsive disorders such as epilepsy.

If a child, their parents or siblings are susceptible to allergic symptoms like hives, bronchial asthma or rash, use this medicine with caution.

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.

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