Mycophenolate Mofetil Capsules TEVA 250 mg for suppressing immune response
What are Mycophenolate Mofetil Capsules TEVA 250 mg for suppressing immune response?
An active principle of this medicine is the mofetil of mycophenolic acid, an immunosuppressive agent. It works by blocking inosine monophosphate dehydrogenase (IMPDH) and, by this, blocking lymphocytes from making guanosine. Mycophenolate Mofetil capsules are effective for the prevention of organ transplant rejection, for treating refractory rejection when the patient does not response to the existing medicines and for treating autoimmune diseases.
Three large-scale clinical trials showed that mycophenolate mofetil significantly reduces the risk of acute rejection after the organ transplantation. Currently, in Japan this medicine is prescribed for suppressing the rejection of renal, heart, liver, lung and pancreas transplantation. The capsules can be used for both adults and children. Mycophenolate Mofetil capsules can be also used for treating autoimmune diseases and similar immune-mediated disorders including Behcet's disease, pemphigus vulgaris, immunoglobulin A nephropathy, small vessel vasculitides, and psoriasis. In these cases the dosage and the duration of the treatment are to be prescribed by your doctor. In Japan, this medicine is often used for the treatment of lupus nephritis as it shows the more frequent complete response.
Active principles: mycophenolate mofetil
Amount: 100 capsules
Maker: Teva Takeda Pharma Ltd., Nagoya, Japan
- inhibiting activity and growth of lymphocytes,
- treating refractory rejection after renal transplantation,
- suppressing rejection of renal, heart, liver, lung, pancreas transplantation,
- treating lupus nephritis.
How to take
For refractory rejection after renal transplantation: adults should take 6 capsules 2 times a day, every 12 hours after meals.
For rejection of renal transplantation: adults should take 4 capsules 2 times a day, every 12 hours after meals. The dosage may be increased up to 12 capsules per day. Children should take 300-600 mg/m2 of the active principle at a time, 2 times a day, every 12 hours after meals. The dosage may be increased up to 8 capsules per day.
For rejection of heart/liver/lung/pancreas transplantation: adults should take 2-6 capsules 2 times a day, every 12 hours after meals.
For lupus nephritis: adults should take 1-4 capsules 2 times a day, every 12 hours after meals. The dosage may be increased up to 12 capsules per day. Children should take 150-600mg/m2 of the active principle at a time, 2 times a day, every 12 hours after meals. The dosage may be increased up to 8 capsules per day.
In case of severe chronic renal failure, the maximum dosage is 4 capsules 2 times a day.
Your doctor may adjust the dosage at any time, according to your disease, age and symptoms.
Contraindications: do not use for patients with digestive system disorder, chronic renal failure, slow recovery for renal function after renal transplantation. Do not use for pregnant, possibly pregnant or breastfeeding women.
Both male and female patients should avoid pregnancy and use birth control while taking this medicine and for 6 weeks after finishing the treatment because it may cause fetal malformation.
Patient should wear protective clothes and use effective sunscreen to avoid sunlight or ultraviolet rays while taking this medication.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.