Iscotin tablets 100 mg for tuberculosis

What are Iscotin tablets 100 mg for tuberculosis?

An active principle of Iscotin tablets is isoniazid, an antibiotic that has been listed by World Health as one the safest and most effective medicines in a healthcare system. It prevents the production of mycolic acid, an essential component of the mycobacterial cell walls. Iscotin tablets can be used to kill both fast-growing and slow-growing bacteria.

Iscotin tablets are effective for both active and latent tuberculosis. For the treatment of the latent form, it is usually sufficient to take this medicine as monotherapy. For active tuberculosis, it is better to use it with rifampicin and pyrazinamide or streptomycin and ethambutol 

One of the most valuable features of Iscotin tablets is their ability to be used for pregnant and breastfeeding women, though with precautions. Japanese specialists do not recommend using isoniazid for the prevention of tuberculosis pregnant and breastfeeding women. For active tuberculosis, Isoctin tablets should be used in a daily dose of 10 mg per kg of body weight for pregnant and breastfeeding women; to minimize the risk of nerve damage, vitamin B6 in its form pyridoxine should be taken concomitantly. The treatment of pregnant and breastfeeding women should only be done under the supervision of a consultant doctor, with consideration of all benefits and risks.

Active principles: isoniazid

Amount: 100 tablets

Maker: Alfresa Pharma Corporation, Osaka, Japan

Indications:

• active form of tuberculosis,
• latent tuberculosis,
• preventing tuberculosis among HIV-positive patients or patients who have a purified protein derivative reaction (PPR) of at least 5 mm in duration
• treatment of atypical mycobacteria types, including M. avium and M. kansasii.

How to take

The usual adult dosage is 200-500 mg (2 to 5 tablets) of isoniazid per day, orally administered in 1 to 3 divided doses, daily or twice a week. If necessary, the daily dose may be increased up to 10 tablets for adults and up to 20 mg/kg for children under 13 years of age. Your doctor can adjust the dosage according to age and symptoms. 

For latent tuberculosis, Iscotin tablets can be used as monotherapy. For active form of tuberculosis, it works better it in combination with other anti-tuberculosis drugs, such as rifampicin and pyrazinamide or streptomycin and ethambutol.  

Contraindications: Do not use in patients suffering from liver, kidney, blood, or convulsing disorder, or alcoholism. Pregnant and breastfeeding women can use this medicine only after discussion of possible risks with their doctor. Patients with mood disorders or depression should take care of possible worsening of their symptoms. 

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.