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Holin 1 mg X 100 tablets (menopause, infertility, hormonal disbalance)

Product Code:
USD 42

What are Holin 1 mg tablets (menopause, infertility, hormonal disbalance)?

Estrogen deficiency causes multiple disease and painful conditions in the female body. It causes changes in cervical mucus composition, leading to cervical hostility. Sperm cannot enter the uterus because of the thick mucus makes, so that leads to infertility. The decrease in hormone levels can cause such unpleasant symptoms as persistent sweating, vaginal mucosal atrophy (itching and discomfort), urinary leakage, depression, anxiety, memory decline, osteoporosis risk, cystitis and atherosclerosis, migraine, and other conditions.

Holin is one the most popular medicines for hormone replacement therapy in Japan. The active principle of these tablets is estriol, a minor female hormone and the most active form of estrogen. Estriol stimulates the work of ovaries in the most gentle way. It maintains hormonal balance and blood flow, and protects the bones from damage. Estriol has a short half-life and a weak connection to estrogen receptors beyond the urogenital system. That's why Holin tablets are safe and have very few side effects. This medication is effective for the treatment of hormonal imbalances, menopause, infertility and some inflammatory diseases in the vaginal and cervical areas.

Active principles: estriol

Amount: 100 tablets

Maker: ASKA Pharmaceutical Co., Ltd., Takeda Pharmaceutical Co., Ltd., Japan


  • Menopause, 
  • vaginitis (senile, pediatric and nonspecific), 
  • cervicitis and cervicovaginal erosion, 
  • senile osteoporosis.

How to take

For menopause, vaginitis (elderly, pediatric and non-specific), cervicitis and cervical erosion: usual adult dosage is 0.1 to 1.0 mg orally 1-2 times a day. Your doctor may adjust the dosage according to your age and symptoms.

For senile osteoporosis: the usual dosage is 1.0 mg orally 2 times a day. Your doctor may adjust the dosage according to your age and symptoms.

Contraindications: do not use for girls under 15 years old, for pregnant or breastfeeding women. Do not use for patients with liver disease. 

Important information

For patients with senile osteoporosis, bone mineral density should be measured 6 months to 1 year after administration. If no effect is observed, discontinue administration and consider other therapies.

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.

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