Glactiv tablets 100 mg for type 2 diabetes - 100 tablets
What are Glactiv (Januvia) tablets 100 mg for type 2 diabetes?
The active principle of Glactiv tablets is sitagliptin. It works by inhibiting the enzyme dipeptidylpeptidase 4(DPP-4). This enzyme is responsible for the breakdown of hormones that stabilize blood glucose levels after meals. By inhibiting this enzyme, insulin production is increased and the blood glucose levels return to normal.
Glactiv tablets provide temporary suppression of the effects of glucagon. This helps to increase the insulin production and to stabilize of the glucose level. The suppression of glucagon is stopped when blood glucose levels returns to normal. This action helps to prevent hypoglycemia in most of cases. Glactiv tablets are not known to cause weight gain and can be taken in conjunction with other medications. Sitagliptin is a safe and generally well-tolerated medicine.
Active principles: sitagliptin phosphate hydrate
Amount: 100 tablets
Maker: Ono Pharmaceutical Co., Ltd., Osaka, Japan
Indications: lowering blood glucose levels in patients with type 2 diabetes mellitus
How to take
For patients with normal renal function or mild renal dysfunction: adults should take 50 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, doctor in charge may increase the dosage up to 1 tablet (100 mg) at a time, once a day, adequately monitoring the condition.
For patients with moderate renal dysfunction: adults should take 25 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, doctor in charge may increase the dosage up to 50 mg at a time, once a day, adequately monitoring the condition.
For patients with severe or end stage renal dysfunction: adults should take 12.5 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, doctor in charge may increase the dosage up to 25 mg at a time, once a day, adequately monitoring the condition.
This medicine contains 100 mg of sitagliptin in one tablet.
Contraindications: do not use for the following patients:
- Patients with ketosis,
- Patients in precoma or diabetic coma,
- Patients with type 1 diabetes,
- Patients with injuries or infections,
- Patients in the pre/postoperative period, or who are debilitated,
- Patients with adrenal gland disorder or pituitary disorder,
- Patients with insufficient diet,
- Patients with a history of abdominal surgery, or intestinal obstruction,
- Patients who exercise intensely or drink a lot of alcohol,
- Breastfeeding or pregnant women.
These tablets may cause hypoglycemic symptoms. Pay close attention when working at heights, driving a car or operating dangerous machinery.
In case of any hypoglycemic symptom, take food or drink that contains enough amount of sugar. If you are taking sitagliptin concomitantly with an α-glucosidase inhibitor, ingest glucose in case of any hypoglycemic symptoms.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.