What are Fycompa tablets 4 mg for epilepsy?
The active principle of Fycompa tablets is perampanel hydrate, a noncompetitive AMPA glutamate receptor antagonist. This substance was developed by Japanese pharmaceutical company Eisai Co. Ltd. and approved in 2012. It is designed for the adjunctive treatment of partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy. Studies showed that 30.9% of patients treated with Fycompa were free of PGTC seizures during the 13 week maintenance period.
Fycompa tablets can be used together with enzyme-inducing antiepileptic drugs or without those. Also, this medicine is suitable for the patients with inadequate response to other antiepileptic agents.
Active principles: perampanel hydrate
Amount: 56 tablets
Maker: Eisai Co., Ltd., Tokyo, Japan
- calming excessively excited nerves in the brain,
- treating partial seizures (including secondary generalized seizures) in epileptic patients,
- treating tonic-clonic attacks in patients with epilepsy,
- suppressing epileptic attacks in epileptic patients with inadequate response to other antiepileptic agents.
How to take
Adults and children 12 years old or more should start with 2 mg of active principle at a time, once a day, before bedtime. Then gradually increase the dosage by the steps of 2 mg with an interval of 1 week or longer between the steps.
If this medicine is taken concomitantly with other antiepileptic agents that promote the metabolism of this medicine, the maintenance dose is 8-12 mg of perampanel once a day. If Fycompa tablets are taken as an only medicine, the maintenance dose is 8 mg once a day.
Your doctor may adjust the dosage according to age and symptoms. However, the maximum daily dose of 12 mg should not be exceeded.
Contraindications: do not use for pregnant or breastfeeding women and patients with liver dysfunction.
As the medicine may cause drowsiness, avoid driving a car, working at heights or operating dangerous machinery while taking this medication.
Avoid taking alcohol and any food or supplement containing St. John's wort while taking these tablets.
If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.