Fluconazole capsules 50 mg for fungemia, candidiasis, mycosis and vaginitis

What are Fluconazole capsules 50 mg for fungemia, candidiasis, mycosis and vaginitis?

Fluconazole is an antifungal medication commonly used in the treatment of various fungal infections, including fungemia, candidiasis, mycosis, and vaginitis. Its mechanism of action primarily involves the inhibition of ergosterol synthesis in the fungal cell membrane, leading to disruption of the membrane's integrity and subsequent cell death. This specificity for fungal cells, rather than human cells, makes Fluconazole an effective treatment for fungal infections.

In cases of fungemia, which is the presence of fungi in the bloodstream, Fluconazole penetrates the fungal cells and interferes with their membrane structure, effectively controlling the spread of the infection. For candidiasis, Fluconazole is effective against various Candida species responsible for localized or systemic infections. Its efficacy in treating candidiasis, particularly in immunocompromised individuals, is well-documented.

Mycosis, a term referring to fungal infections in various body tissues, can be successfully managed with Fluconazole. This medication helps to eradicate the causative fungi, providing relief to patients suffering from mycosis. In cases of vaginitis, where the infection is localized to the vaginal area, oral or topical Fluconazole can be administered. It works by targeting the fungi responsible for the infection, relieving symptoms such as itching and discharge.

Fluconazole's versatility in treating fungal infections extends to individuals of different age groups. It is safe and effective for use in adults, children, and even newborn infants. Dosing adjustments may be required based on age, weight, and the specific infection being treated, but Fluconazole remains a valuable option for healthcare providers in managing fungal infections across the age spectrum.

Active principles: fluconazole

Amount: 20 capsules

Maker: Nihon Generic Co., Ltd., Tokyo, Japan

Indications:

• fungemia, 
• respiratory mycosis, 
• gastrointestinal mycosis, 
• mycosis of urinary tract,
• mycotic meningitis, prevention of deep mycosis in patients undergoing hematopoietic stem cell transplantation,
• vaginitis and vulvovaginitis caused by Candida.

How to take

For candidiasis: adults should take 1-2 capsules (50-100 mg) at a time, once a day. Children should take 3 mg of the active principle per kilogram of the body weight at a time, once a day.

For cryptococcosis: adults should take 1-4 capsules (50-200 mg) at a time, once a day. Children should take 3-6 mg of the active principle per kilogram of the body weight at a time, once a day. 

For severe or refractory fungal infections, the dosage may be increased up to 8 capsules (400 mg) a day for adults, 12 mg per kilogram of the body weight a day for children.

For prevention of deep mycosis in patients undergoing hematopoietic stem cell transplantation: adults should take 8 capsules (400 mg) at a time, once a day. Children should take 12 mg per kg at a time, once a day. However, the maximum daily dose for children is 8 capsules (400 mg).

For vaginitis and vulvovaginitis caused by Candida: adults should take 3 capsules (150 mg) at a time, once.

Newborns of 14 days old or under should receive the same dose of the active ingredient as children every 72 hours. Newborns of 15 days old or over should receive the same dose of the active ingredient as children every 48 hours.

Please note that this preparation contains 50 mg of the active ingredient in 1 capsule.

Contraindications: do not use for patients with renal disorder, liver disorder or heart disease. Do not use for pregnant, possibly pregnant or breastfeeding women. 

Important information

If an allergic reaction occurs, patient needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.