Bonoteo tablets 1 mg for osteoporosis

What are Bonoteo tablets 1 mg for osteoporosis?

Bonoteo tablets contain 1 mg of minodronic acid hydrate, bisphosphonate that inhibits activity of farnesyl pyrophosphate synthase. By this, Bonoteo tablets inhibit osteoclastic bone resorption, 1000 times more effective than etidronic acid and 10 to 100 times more effective than alendronic acid. This medicine decreases the incidence rate of new vertebral and nonvertebral fractures. In other words, it is effective for preventing bone fracture.

Bonoteo tablets are effective for increasing bone density and strength in patients with osteoporosis of different aetiology, including:

• postmenopausal osteoporosis, 
• senile osteoporosis,
• steroid-induced osteoporosis,
• secondary osteoporosis.

Active principles:  minodronic acid hydrate

Amount: 100 tablets

Maker: Astellas Pharma Inc., Tokyo, Japan

Indications: increasing bone density and strength in patients with osteoporosis and preventing bone fracture. 

How to take

Take 1 tablet 1 time a day with approximately 180 ml of water, strictly before the first meal or beverage of the day. At least for the first 30 minutes after taking the tablet, refrain from lying down, eating, drinking (including mineral water) or taking other medicine, except drinking usual water.

Contraindications: Bonoteo tablets cannot be used for the following categories of patients:

• patients with disorder that delays esophageal transit, for example, esophageal stenosis,
• patients unable to sit upright for more than 30 minutes,
• patients with hypocalcemia,
• pregnant or breastfeeding women.

Important information

Never take this medicine after consuming any food or beverages. If you missed the dose and have already had some foods and beverages, skip the missed dose and continue regular intake from the next morning.

Do not crunch or dissolve the medicine in the mouth as it might cause irritation in the mouth or throat. Do not take the medicine at bedtime or before rising. Make sure to take enough calcium and vitamin D from food or vitamin supplements.

If an allergic reaction occurs, patients needs to stop using the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.