ADANT DISPO 25 MG SYRINGE 2.5 ML (joints improving agent)

What are Adant Dispo injections?

Adant Dispo injections contain sodium hyaluronate, the sodium salt of hyaluronic acid, naturally found in various connective tissue of humans and other mammals. When being injected, this substance gets cleared within few hours of injection with a very few adverse effects but it leaves residual effects on contacted cells. That makes Adant Dispo injections safe and effective agent for restoring damaged cells in connective tissues.

Particularly, Adant Dispo injections are used for two main purposes: treatment of knee and hip joints and aqueous and vitreous humor in ophthalmic surgery. When being injected into joint, sodium hyaluronate works as a lubricant and shock absorber, helping to eliminate friction within the joint. When used in surgery in the anterior segment of the eye, Adant Dispo injections help to maintain a deep anterior chamber during surgery, allowing to achieve the result with less trauma to the corneal endothelium and other surrounding tissues. When used in surgery in posterior segment, Adant Dispo helps to gently separate, maneuver and hold tissues.

Active principles: sodium hyaluronate

Full list of components: sodium chloride, sodium hydrogen phosphate dodecahydrate, concentrated hydrochloric acid, sodium hydroxide, water for injection

Amount: 10 syringes x 25 mg

Maker: Meiji Seika Pharma

Indications:

• osteoarthritis and post-traumatic joint changes,
• relief of pain and improvement of joint mobility,
• auxiliary agent in orthopaedic surgery,
• aqueous and vitreous humor in eye surgery.

How to take

Intra-articular injections: The contents of one vial (20 mg/2 ml) or filled syringe (20 mg/2 ml) should be injected into the knee or hip joints once a week. A standard course length is 5 injections, i.e. 5 weeks without interruption.

Intraocular injections: For operations on the anterior segment - the total volume (including repeated injections) usually does not exceed 1 ml; for operations on the posterior segment - 2-4 ml.

Contraindications: Do not use for children, pregnant or breastfeeding women.

Important information

If an allergic reaction occurs, patients needs to stop taking the medicine and consult with their doctor. If patient is taking any other medication or treatment, they should consult with their doctor in advance.

This medicine may cause transient increase in intraocular pressure in the postoperative period with a maximum of 4-8 hours after surgery (due to mechanical blockage of the trabecular meshwork by residual solution).

Since this medicine is injected into the inter-articular space, treatment should only be carried out under sterile conditions. If there is no sign of improvement during the first 5 weeks of use, treatment should be discontinued. If Adant is frozen, let it warm up (at least to room temperature) before use.